Common compounds that are toxic to the Colon.

The colon is the last part of the gastro-intestinal system. Its main function is the re-absorption of water and small molecules, and the compacting of the digesta (gut contents) before elimination from the body.

The Colon is the site of several debilitating diseases; some are inflammatory, some infections and some are cancerous. Problems of the colon are very significant because they affect the mind also and are a major cause of discomfort. Normal functioning of the colon depends on a carefully coordinated process between the neuro-endocrine system and the colon. This process can sometimes be interrupted by several drugs and chemicals.


Here is a list of drugs that can affect Colon function and lead to discomfort;

  • Cocaine-stimulant and drug of addiction.
  • Estrogen-female hormone that is used in contraception, menopause and other indications.
  • Ergotamine-used as migraine medicine and also to stop bleeding of the uterus.
  • Sodium polystyrene-is used in patients with kidney disease to remove excessively high potassium.
  • Vasopressin-is a medicine used in anti-diuretic hormone deficiency. It is also used to control bleeding in the gastro-intestinal tract.
  • Pseudoephedrine-is a stimulant used as a decongestant following nasal congestion.
  • Amphetamines-a stimulant used in the treatment of Narcolepsy, ADHD (Attention Deficit Hyperactivity Disorder) and Obesity.
  • Alosetron-is a restricted drug used in the management of severe Irritable Bowel disease.

These drugs wreak havoc by restricting blood flow to the colon through constricting blood vessels, blood clot formation and the diversion of blood flow away from the colon.

Other toxic compounds that are known to injure the colon include alcohol, carbon tetrachloride and mushroom toxins. Ordinarily, symptoms tend to improve once the offending compound has been removed. Colon health is extremely important for general health maintenance. If the contents of the colon are not eliminated as waste they can become potential toxins.



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